Michael Penix Jr. threw four touchdown passes and No. 5 Washington held off a fierce comeback attempt to beat Stanford 42-33 for its 15th straight win.
The Huskies opened last season 4-0, then lost their first road game to UCLA and took another loss to Arizona State to drop out of the College Football Playoff conversation.
The four remaining Pac-12 schools, California, Stanford, Oregon State and Washington State, will have options if they are looking for another conference.
Stanford's NiJaree Canady outlasted Washington's Ruby Meylan in a battle of Pac-12 freshman pitchers to push the Cardinal into the national semifinals.
March Madness is heading to the Sweet 16! Here is what to know about a women’s NCAA Tournament that has already seen two of the top teams ousted before the regional semifinals:
Endyia Rogers scored 10 of her 28 points in the fourth quarter and ninth-seeded Oregon pulled out a 52-50 win over eighth-seeded Washington in the first round of the Pac-12 Tournament.
Spencer Jones hit four 3-pointers and scored 21 points, Brandon Angel added 14 points, as Stanford beat Washington 81-69 to snap a three-game losing streak.
South Carolina, Stanford and LSU are the top teams in the latest women's AP Top 25 college basketball rankings. South Carolina is No. 1 for the 32nd consecutive week.